| #1 |  | York and Scarborough Teaching Hospital NHS Foundation Trust | 8,909.5 km | 675 | 133 | |
| #2 |  | Leeds Teaching Hospitals NHS Trust | 7,238.9 km | 887 | 188 | |
| #3 |  | Mid Yorkshire Hospitals NHS Trust | 6,828.3 km | 885 | 169 | |
| #4 |  | Chesterfield Royal Hospital NHS Foundation Trust | 6,294.0 km | 776 | 127 | |
| #5 |  | NHS Blood and Transplant - Yorkshire | 3,033.2 km | 384 | 61 | |
| #6 |  | Calderdale and Huddersfield NHS Foundation Trust | 2,507.0 km | 197 | 40 | |
| #7 |  | NHSBT Bradford Donor Centre | 2,288.2 km | 299 | 52 | |
| #8 |  | NHSBT - Leeds City DC | 2,001.7 km | 256 | 36 | |
| #9 |  | Bradford Teaching Hospitals NHS Foundation Trust | 1,606.0 km | 153 | 33 | |
| #10 |  | UECC-Rotherham Foundation Trust | 1,458.2 km | 63 | 12 | |
| #11 |  | Hull and East Yorkshire Hospitals NHS Trust | 1,331.7 km | 122 | 31 | |
| #12 |  | Sheffield Teaching Hospitals NHS Foundation Trust | 1,157.4 km | 71 | 13 | |
| #13 |  | United Lincolnshire Hospitals NHS Trust | 882.3 km | 134 | 33 | |
| #14 |  | Doncaster and Bassetlaw Hospitals NHS Foundation Trust | 661.8 km | 100 | 30 | |
| #15 |  | Harrogate and District NHS Foundation Trust | 561.4 km | 45 | 10 | |
| #16 |  | The Rotherham NHS Foundation Trust | 441.6 km | 61 | 20 | |
| #17 |  | Audit Yorkshire | 215.6 km | 43 | 8 | |
| #18 |  | Airedale NHS Foundation Trust | 138.8 km | 20 | 4 | |
| #19 |  | Kingstone Runners | 108.8 km | 20 | 5 | |
| #20 |  | Northern Lincolnshire and Goole Hospitals NHS Foundation Trust | 80.4 km | 10 | 1 | |
| #21 |  | Sheffield Children's NHS Foundation Trust | 48.0 km | 2 | 2 | |
| #22 |  | Barnsley Hospital NHS Foundation Trust | 12.9 km | 1 | 1 | |
| #23 |  | The Avie Girls | 2.0 km | 1 | 2 | |